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Importantly, darker skin phototypes exhibit greater resistance to UVB-induced cytotoxicity due to higher eumelanin levels, while UVA-induced effects may be influenced by the phototoxic potential of pheomelanin in lighter skin 13

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For most patients with vitamin B12 deficiency, high-dose oral supplements are as effective as intramuscular injections at raising serum B12 levels and resolving symptoms

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